Health Benefits of Chlorogenic Acid Coffee
Coffee is a popular drink all over the world. Chlorogenic acid coffee sales are also growing rapidly with an annual increase of 15% to 20%. Because it can refresh the brain, can let a person for a short time drive away sleepy, also workers affectionately known as a “renewal of life magic weapon”.
Many weight loss bloggers say: that weight loss should drink more black coffee because black coffee helps to lose fat. Is this true? If it is true, why can black coffee help you lose weight?
In fact, coffee does help with fat loss because it promotes defecation, diuresis, and appetite suppression, and also improves cellular autophagy and antioxidants, which helps with fat loss. Not only that, but coffee accelerates ketogenesis and also improves insulin sensitivity, and many studies have found that the more coffee you drink, the lower your risk of developing type 2 diabetes.
Some people say it’s all about caffeine, but it’s not, caffeine does boost your energy, but what gives coffee these amazing effects is the chlorogenic acid in coffee.
What Is Chlorogenic Acid?
Chlorogenic acid in coffee is an important phenolic compound that has a variety of positive effects on human health.
Chlorogenic acid is a condensed phenolic acid produced from caffeic acid and quinic acid, which are polyphenols. Polyphenols are generally known to have strong antioxidant properties, and chlorogenic acid is also a potent phenolic antioxidant, and its antioxidant capacity is stronger than many other phenolic compounds.
It is widely found in plants such as honeysuckle, sunflower, coffee, and cocoa trees, as well as fruits such as apples and pears, and vegetables such as potatoes, carrots, soybeans, wheat, and green tea.
Although chlorogenic acid was discovered by modern medicine, there is a long tradition of utilizing it in medicine. Honeysuckle, for example, has been famous for its wide range of medicinal values since ancient times. Modern research has proven that honeysuckle contains chlorogenic acid, which has a strong inhibitory effect on many bacteria, and one of its antibacterial and antiviral effective pharmacological components is chlorogenic acid.
What Are The Benefits of Chlorogenic Acid?
Chlorogenic acid is an important bioactive substance with antibacterial, antiviral, hypotensive, hypolipidemic, free radical scavenging, and weight loss effects.
→ Fat reduction, weight management
An experiment on the anti-obesity of chlorogenic acid found that chlorogenic acid has anti-obesity properties and improved lipid metabolism in obese mice.
The results of the trial showed that chlorogenic acid significantly reduced body weight, visceral fat mass, plasma leptin and insulin levels, triglycerides in the liver and heart, and cholesterol in adipose tissue and heart.
In another human trial, chlorogenic acid-rich coffee was found to induce a 6.9% reduction in glucose uptake, which may lead to weight and body fat loss if used for an extended time.
Chlorogenic acid reduces body fat through several mechanisms, including inhibiting fatty acid synthase activity, promoting triacylglycerol hydrolase activity, and increasing cholesterol excretion. Moreover, by lowering the triglyceride content of the liver, chlorogenic acid also has a hepatoprotective effect and significantly reduces the severity of pathological liver damage.
→ Inhibits insulin resistance and lowers blood sugar
Multiple epidemiologic and experimental data suggest that chlorogenic acid prevents diet-induced hepatic steatosis and insulin resistance. A human study found that drinking chlorogenic acid-rich coffee reduced hepatic insulin resistance.
Chlorogenic acid regulates blood glucose on the principle that it significantly inhibits alpha-amylase activity, reducing starch digestion and delaying the rapid rise in postprandial blood glucose.
Chlorogenic acid also activates AMP-activated protein kinase (AMPK), which is the master sensor and regulator of cellular energy homeostasis and is associated with improved glucose and lipid metabolism.
→ Antioxidant
There is a strong correlation between oxidative stress and the development of a variety of degenerative diseases, including neurodegenerative and other aging-related diseases and even cancer.
The healthful properties of chlorogenic acid derive from its multiple biological activities, such as antioxidant, antiviral, antibacterial, anticancer, and anti-inflammatory activities.
Chlorogenic acid’s antioxidant is similar to vitamin C in scavenging free radicals, and it also regulates gene expression of antioxidant enzymes.
Chlorogenic acid also chelates transition metals, inhibits the formation of reactive oxygen species, and plays a beneficial role in the prevention of oxidative and aging-related diseases.
→ Antimicrobial, anti-inflammatory
Inflammation is tissue damage caused by exogenous or endogenous sources, and prolonged uncontrolled inflammatory processes can induce many chronic conditions such as diabetes, and cardiovascular and neurodegenerative diseases.
Chlorogenic acid regulates key transcription factors such as tumor necrosis factor-alpha (TNF-α) and interleukins (e.g., IL-8) and has anti-inflammatory activity by reducing pro-inflammatory cytokines. Because of its high antioxidant and anti-inflammatory activity, it has a cardiovascular protective effect, enhancing cardiac function and reducing lipid peroxidation and ROS levels in cardiomyocytes.
In addition to this, because of its special inhibitory effect on hyaluronidase, chlorogenic acid is effective for trauma healing, moisturizing the skin, and lubricating the joints.
Chlorogenic acid also has a strong inhibitory and killing effect on a variety of bacteria and viruses, which is also an effective antibacterial component of the traditional Chinese medicine honeysuckle, combined with antibiotics synergistic antibacterial will be more effective.