How Exactly Do Lipids Change During Low Carb
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How Exactly Do Lipids Change During Low Carb?

The changes in blood lipids after going low carb may scare a lot of people, including doctors. Generally, after a low-carb ketogenic diet, after having a lipid test done, elevated cholesterol and elevated LDL are detected.

We all know that in a traditional diet (high carb) state, the body’s cells rely primarily on glucose for energy. Normally, glucose ‘swims’ in the bloodstream, and the cells ‘grab’ glucose from the bloodstream and ‘eat’ it.

Where does this glucose come from? All kinds of rice, noodles, sugar, and other high-carbohydrate foods that you eat in your daily life are quickly broken down and converted into glucose when they enter the intestines. If, however, you start a low-carb diet, there will be less glucose in your body or even a shortage.

At this point, another type of energy is ‘awakened’, what is it? It is fat. However, fat is not soluble in water, so it is impossible to go to the blood for energy by itself. Wouldn’t it be perfect if there was a ‘boat’ that could carry fat and swim freely in the blood?

Where does this glucose come from

There is, and it’s called lipoprotein. The bad cholesterol on the test data is a type of lipoprotein (LDL low-density lipoprotein). There are a variety of lipoprotein sizes, from the largest, VLDL, to the middle, ILDL, to the smaller LDL LDL.

Generally, after 12 hours of fasting, celiac is largely consumed and undetectable, so it’s usually just ignored. After low carb, sugar is depleted and fat supply begins, giving cellular function in the form of triglycerides, and transporting triglycerides in the ship of lipoproteins.

Lipoproteins are not only “triglycerides”, but also “fat-soluble vitamins” (vitamins A, D, E, K), and also loaded with a bunch of lifeboats, i.e. “cholesterol”. This fully loaded boat (lipoproteins) starts in the liver, carries triglycerides into the bloodstream to energize the cells with fat, and then returns to the liver.

During a low-carb diet, when the cells need a lot of fat energy, the LDL is going to be busier than usual, with a lot of LDL loaded with a lot of ‘triglycerides’ traveling through the bloodstream, delivering fat to the cells.

Antiphase Mode of Blood Lipids

When you massively increase your fat intake, three days later, you will instead detect a drop in blood cholesterol and LDL. Now that I think about it, this is not by chance, but because: the fat you eat, is metabolized in the intestine to celiac particles, the largest particles of fat, which can also provide the body with energy.

The scene in the bloodstream at this time is that a large number of celiac particles energize the cells, and the LDL in the bloodstream decreases. The greatest significance of this inverse pattern is that it proves that the current fat-feeding of the ketogenic diet and the change in blood lipids is due to an increase in LDL.

Antiphase Mode of Blood Lipids

→ Another explanation is, the gene expression of LDL receptors

A large caloric intake or elevated insulin levels increase the gene expression of the LDL receptor, allowing more LDL to move out of the circulation and into the liver. Even statins work in the same way, increasing the gene expression of the receptor, and transferring LDL from the circulation to the liver.

→ Free control of all your lipids levels

If you want to control your LDL level freely, you can do so in the following ways:

  • Three days before the test, start to consume a lot of fat, as much as you can and eat as much as you can, through calories, to stimulate the gene expression of the LDL receptor, so that more LDL is transferred from the blood circulation.
  • Eating some carbohydrates to stimulate insulin will also increase gene expression at the receptor and lower LDL. Because gene expression is not a fast feedback, it usually takes three days to see the feedback.
  • Don’t fast for too long, for example, for an 8:00 a.m. blood test, you could have a meal in the middle of the night and then go to bed. It has been found that fasting for more than 12 hours directly raises LDL levels because fasting lowers insulin levels and reduces gene expression of LDL receptors.

Why Doctors Fear High LDL Levels?

There is no problem with the theory that high LDL levels are indeed risky in a time when everyone is on a high-carb diet, and in the long run, they tend to cause blood vessel blockages. So why does LDL, which is supposed to be a transport ship, turn out to be bad?

LDL turns bad when it runs into a bad neighbor, which is sugar, and when blood sugar is high, LDL levels are also high, as are triglycerides, which means that the blood is in a state of excess energy. At this time, LDL is easily glycated and can turn into very bad LDL that may cross the walls of blood vessels and cause atherosclerosis.

Why Doctors Fear High LDL Levels

This is because, glycated LDL, increases the permeability of the cell membrane and becomes porous and easily permeable. Once they cross this membrane, they may hang out with a type of cell called a macrophage. These macrophages have a receptor called a scavenger receptor, and these receptors only recognize oxidized LDL.

Then, when the macrophages are filled with destroyed LDL, they become foam cells, which eventually lead to blood vessel blockage. This is how glycated LDL, blocks blood vessels.

This is why, glycated hemoglobin, and high blood sugar an important indicators of heart health because high blood sugar makes LDL bad and eventually leads to blockage of blood vessels. This is why many people with diabetes, tend to be prone to clogged blood vessels and heart disease is a complication of diabetes.

How To Tell Your Blood Lipids After Keto

Regarding how to determine your lipid profile, Paul Mason from Australia gives a few tips on how to check your lipid profile after ketogenic.

First of all, if you have low triglycerides, then there is no problem and you can rest assured. If triglycerides are not low, then you go to a good cholesterol (HDL) level, and if it’s greater than 1.5, then you can rest assured as well. Finally, you can also refer to the ratio between them and if it is less than 0.8, you can also rest assured.

How To Tell Your Blood Lipids After Keto

Normally, after a period of low carb, triglycerides will be very low, and there are also individual cases where the triglyceride indicator has not come down for a while, for several reasons. As I said before, after a low-carbon diet, LDL will deliver a large amount of loaded “triglycerides” to the cells for energy consumption. As a result, when you take a blood test, you will generally find that your triglycerides are dropping.

Also, an increase in dietary fat may temporarily raise triglycerides in the blood a little. But as long as you’re not over-consuming more fat than your cells need, total triglyceride levels will go down on a low-carb ketogenic diet.

If none of these are accurate and you’re still concerned, you can get a glycated hemoglobin test, a cardiac calcification test, and an inflammation index test, all of which are important indicators of heart disease.

Anyway, you can check your blood lipids and other indicators regularly to observe their changes.

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